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Tay-Sachs, Canavan, GM1 and Sandhoff diseases

About Inheritance

Autosomal Recessive Inheritance

Tay-Sachs disease, GM-1 and several other allied diseases are autosomal recessive. For recessive conditions, both parents must be carriers for a child to be at risk of inheriting the disease. A carrier has one working copy and one non-working copy of a given gene pair. Males and females are affected equally and carriers are not expected to have adverse health effects.






X-linked Inheritance