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Latest Tay Sachs Disease News and Research

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children
A study aiming to develop a new therapeutic technique could bring a revolution in our approach to treating rare, fatal Sanfilippo syndrome, a disorder that affects children as young as 2 years old and leads to childhood dementia and premature death.
Study underscores the need for more precise rare disease definitions
Some diseases are like black swans. They occur so rarely that many physicians never encounter them in their clinical practice, complicating efforts to treat them.
New CRISPR genome “prime editing” system
Gene editing to correct genetic faults and removing the risk of hereditary diseases may soon become reality. Researchers have come up with a new gene editing technology that could help patients with sickle cell anaemia and up 89 percent of other genetic defects.

Latest Sandhoff Disease News and Research

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children
A study aiming to develop a new therapeutic technique could bring a revolution in our approach to treating rare, fatal Sanfilippo syndrome, a disorder that affects children as young as 2 years old and leads to childhood dementia and premature death.
New drug lures stem cells to damaged tissue, improves treatment efficacy
Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a drug that can lure stem cells to damaged tissue and improve treatment efficacy--a scientific first and major advance for the field of regenerative medicine.
Gene therapy is the best stratagem to impact the course of GM2 gangliosidosis
Since its clinical description in 1881, Tay-Sachs disease has had almost totemic significance as a cruel and relentless genetic condition that destroys the developing brain of babies and young children.

Latest Canavan Disease (Leukodystrophies) News and Research

Human stem cells show promise against fatal children's diseases
Scientists have used human stem cells to dramatically improve the condition of mice with a neurological condition similar to a set of diseases in children that are invariably fatal, according to an article in the June issue of the journal Cell Stem Cell.

Visit our library of eNews for copies of past newsletters, research updates, topics of the week and more

Geneticist Ricki Lewis blogs from the cutting edge of genomics, including genetic testing, stem cells, gene therapy and more.

3 Possible Origins of COVID: Lab Escapee, Evolution, or Mutator Genes?

“Virus outbreak: research says COVID-19 likely synthetic,” shouted the headline in the Taipei Times on February 23, 2020. The idea that the…

The post 3 Possible Origins of COVID: Lab Escapee, Evolution, or Mutator Genes? appeared first on DNA Science.
Huntington’s Disease: 2 Steps Backward, 1 Step Forward

Last week’s DNA Science post considered the ebb and flow of treatment possibilities for Alzheimer’s disease. This week, it’s Huntington’s disease. Like…

The post Huntington’s Disease: 2 Steps Backward, 1 Step Forward appeared first on DNA Science.
Alzheimer’s Treatments in the Pipeline and the False Promise of Prevagen: Distinguishing Hope from Hype

The avalanche of TV ads for Prevagen that coincided with my reaching Medicare age has inspired me to investigate what’s coming for…

The post Alzheimer’s Treatments in the Pipeline and the False Promise of Prevagen: Distinguishing Hope from Hype appeared first on DNA Science.

Latest Gangliosidosis News and Research

Gene therapy is the best stratagem to impact the course of GM2 gangliosidosis
Since its clinical description in 1881, Tay-Sachs disease has had almost totemic significance as a cruel and relentless genetic condition that destroys the developing brain of babies and young children.
New gene therapy shows promising results for treating neurodegenerative disorders
A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains of treated mice, restored enzyme function, and extended survival by about 2.5-fold.
Researchers devise new genetic technique for IVF embryos
Researchers at the Johns Hopkins University School of Medicine have devised a new technique, which helps couples that are affected by or are carriers of genetic diseases have in vitro fertilized babies free of both the disease in question and other chromosomal abnormalities. The results were reported in the April issue of Fertility and Sterility.