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Tay-Sachs, Canavan, GM1 and Sandhoff diseases


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Term Definition

A type of fat (lipid) molecule accumulates in individuals with Gaucher disease and is used as a building block to make certain cell membranes. When the cells wear out, the glucocerebroside can be recycled. This recyclable material comes mainly from the breakdown of old red and white blood cells. In the brain, glucocerebroside comes from the processing of lipids during brain development and the formation of the myelin sheath (the fatty coating around each nerve fiber).

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